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Bile acid / gallbladder flow in the sample report

This page explains why this pathway rose in the sample report, what it likely means, and what to validate next.

Worth checking now

What stands out

This is a meaningful pathway in the sample.

What it likely means

Working interpretation

The working read here is lower bile acid / gallbladder flow support.

What to check next

Key markers

GGT, bilirubin, fat intolerance context

How much to care

Priority context

High. This is one of the clearest and most testable findings in the report.

Why it rose

Why this pathway surfaced

This pathway tends to surface when several studied variants in its core genes point in a similar direction strongly enough to justify biomarker follow-up.

7 genes reviewed · 18 variant rows

GGT

gives context on detox burden, bile flow, and liver stress

bilirubin

Bilirubin gives practical context for whether bile acid / gallbladder flow is showing up in real physiology.

fat intolerance context

Fat intolerance context gives practical context for whether bile acid / gallbladder flow is showing up in real physiology.

Open report sectionOpen evidence appendixOpen evergreen topic guide

Main genes

Which genes are carrying the signal

ABCB11

Supporting contributor · Medium confidence

ABCB11 adds weight to the same pathway interpretation, but does not drive it alone.

ABCB11 adds bile acid / gallbladder flow context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

ABCG8

Supporting contributor · Medium confidence

ABCG8 adds weight to the same pathway interpretation, but does not drive it alone.

ABCG8 adds bile acid / gallbladder flow context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

CYP7A1

Supporting contributor · Medium confidence

CYP7A1 adds weight to the same pathway interpretation, but does not drive it alone.

CYP7A1 adds bile acid / gallbladder flow context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

SLC10A1

Supporting contributor · Medium confidence

SLC10A1 adds weight to the same pathway interpretation, but does not drive it alone.

SLC10A1 adds bile acid / gallbladder flow context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

PNPLA3

Supporting contributor · Medium confidence

PNPLA3 adds weight to the same pathway interpretation, but does not drive it alone.

PNPLA3 adds bile acid / gallbladder flow context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

TM6SF2

Supporting contributor · Medium confidence

TM6SF2 adds weight to the same pathway interpretation, but does not drive it alone.

TM6SF2 adds bile acid / gallbladder flow context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix