What stands out
This is one of the clearest secondary pathways in the sample.
Working interpretation
The working read here is lower phase ii detox / clearance support.
Key markers
Bilirubin, GGT, liver enzyme context
Priority context
High. This is one of the clearest and most testable findings in the report.
Why it rose
Why this pathway surfaced
This pathway tends to surface when several studied variants in its core genes point in a similar direction strongly enough to justify biomarker follow-up.
Bilirubin
gives context on conjugation and clearance load in the liver
GGT
gives context on detox burden, bile flow, and liver stress
liver enzyme context
helps show whether the clearance signal is surfacing in routine liver-related markers
Main genes
Which genes are carrying the signal
GSTP1
GSTP1 adds weight to the same pathway interpretation, but does not drive it alone.
GSTP1 adds phase ii detox / clearance context and should be interpreted with the surrounding pathway pattern, not on its own.
GSTT1
GSTT1 adds weight to the same pathway interpretation, but does not drive it alone.
GSTT1 adds phase ii detox / clearance context and should be interpreted with the surrounding pathway pattern, not on its own.
CYP1A2
CYP1A2 adds weight to the same pathway interpretation, but does not drive it alone.
CYP1A2 adds phase ii detox / clearance context and should be interpreted with the surrounding pathway pattern, not on its own.
GSTM1
GSTM1 adds weight to the same pathway interpretation, but does not drive it alone.
GSTM1 adds phase ii detox / clearance context and should be interpreted with the surrounding pathway pattern, not on its own.
CYP1B1
CYP1B1 adds weight to the same pathway interpretation, but does not drive it alone.
CYP1B1 adds phase ii detox / clearance context and should be interpreted with the surrounding pathway pattern, not on its own.