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Sleep / circadian regulation in the sample report

This page explains why this pathway rose in the sample report, what it likely means, and what to validate next.

Worth checking now

What stands out

This is a meaningful pathway in the sample.

What it likely means

Working interpretation

The working read here is lower sleep / circadian regulation support.

What to check next

Key markers

melatonin timing, sleep regularity, recovery pattern

How much to care

Priority context

High. This is one of the clearest and most testable findings in the report.

Why it rose

Why this pathway surfaced

This pathway tends to surface when several studied variants in its core genes point in a similar direction strongly enough to justify biomarker follow-up.

7 genes reviewed · 18 variant rows

melatonin timing

Melatonin timing gives practical context for whether sleep / circadian regulation is showing up in real physiology.

sleep regularity

Sleep regularity gives practical context for whether sleep / circadian regulation is showing up in real physiology.

recovery pattern

Recovery pattern gives practical context for whether sleep / circadian regulation is showing up in real physiology.

Open report sectionOpen evidence appendixOpen evergreen topic guide

Main genes

Which genes are carrying the signal

MTNR1A

Supporting contributor · Medium confidence

MTNR1A adds weight to the same pathway interpretation, but does not drive it alone.

MTNR1A adds sleep / circadian regulation context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

ASMT

Supporting contributor · Medium confidence

ASMT adds weight to the same pathway interpretation, but does not drive it alone.

ASMT adds sleep / circadian regulation context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

CLOCK

Supporting contributor · Medium confidence

CLOCK adds weight to the same pathway interpretation, but does not drive it alone.

CLOCK adds sleep / circadian regulation context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

PER3

Supporting contributor · Medium confidence

PER3 adds weight to the same pathway interpretation, but does not drive it alone.

PER3 adds sleep / circadian regulation context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

ADORA2A

Supporting contributor · Medium confidence

ADORA2A adds weight to the same pathway interpretation, but does not drive it alone.

ADORA2A adds sleep / circadian regulation context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix

MTNR1B

Supporting contributor · Medium confidence

MTNR1B adds weight to the same pathway interpretation, but does not drive it alone.

MTNR1B adds sleep / circadian regulation context and should be interpreted with the surrounding pathway pattern, not on its own.

Open gene pageOpen appendix